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Recombinant Human L antigen family member 3 (LAGE3)

ACP18470

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18470 Target NameLAGE3
Target SynonymsLAGE3; DXS9879E; ESO3; ITBA2EKC/KEOPS complex subunit LAGE3; L antigen family member 3; Protein ESO-3; Protein ITBA2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-143
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ14657
Background Information
  • Uniprot Id

    Q14657

  • Target Species

    Human

  • Target Name

    LAGE3

  • Target Full Name

    EKC/KEOPS complex subunit LAGE3

  • Target Function

    Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. LAGE3 functions as a dimerization module for the complex.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    CTAG/PCC1 family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    LAGE3; DXS9879E; ESO3; ITBA2EKC/KEOPS complex subunit LAGE3; L antigen family member 3; Protein ESO-3; Protein ITBA2

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