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| Cat.No | ACP18814 | Target Name | TMEM5 |
|---|---|---|---|
| Target Synonyms | HP10481; Putative type II membrane protein; TMEM5; TMEM5_HUMAN; Transmembrane protein 5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y2B1 |
|---|
Uniprot Id
Q9Y2B1
Target Species
Human
Target Name
RXYLT1
Target Full Name
Ribitol-5-phosphate xylosyltransferase 1
Target Function
UDP-xylosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan.
Target Involvement
Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A10 (MDDGA10)
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
RXYLT1 family
Target Synonyms
HP10481; Putative type II membrane protein; TMEM5; TMEM5_HUMAN; Transmembrane protein 5
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