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Recombinant Human Transmembrane protein 5 (TMEM5), Truncated

ACP18814

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18814 Target NameTMEM5
Target SynonymsHP10481; Putative type II membrane protein; TMEM5; TMEM5_HUMAN; Transmembrane protein 5FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9Y2B1
Background Information
  • Uniprot Id

    Q9Y2B1

  • Target Species

    Human

  • Target Name

    RXYLT1

  • Target Full Name

    Ribitol-5-phosphate xylosyltransferase 1

  • Target Function

    UDP-xylosyltransferase involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Acts as a UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase, which catalyzes the transfer of UDP-D-xylose to ribitol 5-phosphate (Rbo5P) to form the Xylbeta1-4Rbo5P linkage on O-mannosyl glycan.

  • Target Involvement

    Muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies A10 (MDDGA10)

  • Target Subcellular Location

    Golgi apparatus membrane; Single-pass type II membrane protein.

  • Target Protein Families

    RXYLT1 family

  • Target Synonyms

    HP10481; Putative type II membrane protein; TMEM5; TMEM5_HUMAN; Transmembrane protein 5

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