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| Cat.No | ACP18981 | Target Name | GRHPR |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-328 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9UBQ7 |
|---|
Uniprot Id
Q9UBQ7
Target Species
Human
Target Name
GRHPR
Target Full Name
Glyoxylate reductase/hydroxypyruvate reductase
Target Function
Enzyme with hydroxy-pyruvate reductase, glyoxylate reductase and D-glycerate dehydrogenase enzymatic activities. Reduces hydroxypyruvate to D-glycerate, glyoxylate to glycolate oxidizes D-glycerate to hydroxypyruvate.
Target Involvement
Hyperoxaluria primary 2 (HP2)
Target Protein Families
D-isomer specific 2-hydroxyacid dehydrogenase family
Target Tissue Specificity
Ubiquitous. Most abundantly expressed in the liver.
Target Synonyms
GLXR; glycerate 2 dehydrogenase ; GLYD; Glyoxylate reductase/hydroxypyruvate reductase; Grhpr; GRHPR_HUMAN; OTTHUMP00000021379; OTTHUMP00000021380; OTTHUMP00000046131; PH 2; PH2; Primary hyperoxaluria type 2
Target Background
This gene encodes an enzyme with hydroxypyruvate reductase, glyoxylate reductase, and D-glycerate dehydrogenase enzymatic activities. The enzyme has widespread tissue expression and has a role in metabolism. Type II hyperoxaluria is caused by mutations in this gene.
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