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Recombinant Human Zinc finger protein 431 (ZNF431)

ACP19397

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP19397 Target NameZNF431
Target SynonymsZNF431; KIAA1969; Zinc finger protein 431FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-576
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TF32
Background Information
  • Uniprot Id

    Q8TF32

  • Target Species

    Human

  • Target Name

    ZNF431

  • Target Full Name

    Zinc finger protein 431

  • Target Function

    Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    Krueppel C2H2-type zinc-finger protein family

  • Target Synonyms

    ZNF431; KIAA1969; Zinc finger protein 431

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