Home Products Uncategorized Recombinant Human Centromere protein Q (CENPQ)

Recombinant Human Centromere protein Q (CENPQ)

ACP19626

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Specifications

Cat.No	ACP19626	Target Name	CENPQ
Target Synonyms	CENP Q; CENP-Q; Cenpq; CENPQ_HUMAN; Centromere protein Q; FLJ10545; OTTHUMP00000016579	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-268
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q7L2Z9

Background Information

Uniprot Id

Q7L2Z9
Target Species

Human
Target Name

CENPQ
Target Full Name

Centromere protein Q
Target Function

Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Plays an important role in chromosome congression and in the recruitment of CENP-O complex (which comprises CENPO, CENPP, CENPQ and CENPU), CENPE and PLK1 to the kinetochores.
Target Subcellular Location

Nucleus. Chromosome, centromere. Note=Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Target Protein Families

CENP-Q/OKP1 family
Target Synonyms

CENP Q; CENP-Q; Cenpq; CENPQ_HUMAN; Centromere protein Q; FLJ10545; OTTHUMP00000016579
Target Background

CENPQ is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al., 2006 [PubMed 16622420]).

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Recombinant Human Centromere protein Q (CENPQ)

Specifications

Immunogen Information

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