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Recombinant Human Microsomal triglyceride transfer protein large subunit (MTTP), Truncated

ACP22849

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Specifications

Cat.No	ACP22849	Target Name	MTTP
Target Synonyms	mitochondrial, proline; tRNA-Pro	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P55157

Background Information

Uniprot Id

P55157
Target Species

Human
Target Name

MTTP
Target Full Name

Microsomal triglyceride transfer protein large subunit
Target Function

Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the assembly and secretion of plasma lipoproteins that contain apolipoprotein B. May be involved in regulating cholesteryl ester biosynthesis in cells that produce lipoproteins.
Target Involvement

Abetalipoproteinemia (ABL)
Target Subcellular Location

Endoplasmic reticulum. Golgi apparatus.
Target Tissue Specificity

Liver and small intestine. Also found in ovary, testis and kidney.
Target Synonyms

ABL; Microsomal triglyceride transfer protein (large polypeptide 88kDa); Microsomal triglyceride transfer protein 88kD; Microsomal triglyceride transfer protein; Microsomal triglyceride transfer protein large subunit; MTP; MTP large subunit; MTP_HUMAN; MTTP; Transfer RNA, mitochondrial, proline; tRNA-Pro, mitochondrial
Target Background

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

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Recombinant Human Microsomal triglyceride transfer protein large subunit (MTTP), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Microsomal triglyceride transfer protein large subunit (MTTP), Truncated Now

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