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| Cat.No | ACP22950 | Target Name | ARFIP1 |
|---|---|---|---|
| Target Synonyms | ADP ribosylation factor interacting protein 1; ADP-ribosylation factor-interacting protein 1; Arfaptin; Arfaptin-1; ARFIP 1; Arfip1; ARFP1_HUMAN; HSU52521; MGC117369 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-373 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P53367 |
|---|
Uniprot Id
P53367
Target Species
Human
Target Name
ARFIP1
Target Full Name
Arfaptin-1
Target Function
Plays a role in controlling biogenesis of secretory granules at the trans-Golgi network. Mechanisitically, binds ARF-GTP at the neck of a growing secretory granule precursor and forms a protective scaffold. Once the granule precursor has been completely loaded, active PRKD1 phosphorylates ARFIP1 and releases it from ARFs. In turn, ARFs induce fission. Through this mechanism, ensures proper secretory granule formation at the Golgi of pancreatic beta cells.
Target Subcellular Location
Golgi apparatus. Golgi apparatus, trans-Golgi network membrane.
Target Tissue Specificity
Ubiquitously expressed. Higher levels in liver, pancreas, placenta, skeletal muscle and heart.
Target Synonyms
ADP ribosylation factor interacting protein 1; ADP-ribosylation factor-interacting protein 1; Arfaptin; Arfaptin-1; ARFIP 1; Arfip1; ARFP1_HUMAN; HSU52521; MGC117369
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