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| Cat.No | ACP23311 | Target Name | MYCNOS |
|---|---|---|---|
| Target Synonyms | MYCNOS; CYMN; NCYM; N-cym protein; N-myc opposite strand | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-109 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P40205 |
|---|
Uniprot Id
P40205
Target Species
Human
Target Name
MYCNOS
Target Full Name
N-cym protein
Target Function
Regulates stability of MYCN in neuroblastoma cells by inhibiting GSK3B-mediated MYCN phosphorylation. Inhibits GSK3B activity by promoting its phosphorylation at 'Ser-9'.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Tissue Specificity
Expressed in the neuronal cells of the cerebrum and cerebellum, spermatocytes of the testis, pancreatic cells and also the heart. Expressed in both primary and metastatic neuroblastomas and in thyroid tumors (at protein level). Expression is associated wi
Target Synonyms
MYCNOS; CYMN; NCYM; N-cym protein; N-myc opposite strand
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