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The antibody against SLC39A4 was raised in rabbit using the Recombinant Human Zinc transporter ZIP4 protein (26-266aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against SLC39A4 was raised in rabbit using the Recombinant Human Zinc transporter ZIP4 protein (26-266aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
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Western Blot | Positive WB detected in: COLO320 whole cell lysate, Mouse Kidney tissue | All lanes: SLC39A4 antibody at 1:2000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 69, 67 kDa | Observed band size: 69 kDa
| Cat.No | ADC-54917A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SLC39A4 |
| Target Synonyms | SLC39A4; ZIP4; Zinc transporter ZIP4; Solute carrier family 39 member 4; Zrt- and Irt-like protein 4; ZIP-4 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Zinc transporter ZIP4 protein (26-266aa) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6P5W5 |
Uniprot Id
Q6P5W5
Target Species
Human
Target Name
SLC39A4
Target Full Name
Zinc transporter ZIP4
Target Function
Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability.
Target Involvement
Acrodermatitis enteropathica, zinc-deficiency type (AEZ)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
Target Protein Families
ZIP transporter (TC 2.A.5) family
Target Tissue Specificity
Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum.
Target Synonyms
SLC39A4; ZIP4; Zinc transporter ZIP4; Solute carrier family 39 member 4; Zrt- and Irt-like protein 4; ZIP-4
Target Background
This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica. Multiple transcript variants encoding different isoforms have been found for this gene.
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