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The antibody against nos was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) nos protein (211-401aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
The antibody against nos was raised in rabbit using the Recombinant Drosophila melanogaster (Fruit fly) nos protein (211-401aa) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
$299.00
Western Blot | Positive WB detected in: recombinant protein | All lanes: nos Antibody at 1:1000 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 38 kDa | Observed band size: 38 kDa
| Cat.No | ADC-55391A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | nos |
| Target Synonyms | Protein nanos nos CG5637 | Form | Liquid |
| Species Reactivity | Drosophila melanogaster (Fruit fly) | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | Affinity-chromatography purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Drosophila melanogaster (Fruit fly) nos protein (211-401aa) | Target Species | Drosophila melanogaster (Fruit fly) |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P25724 |
Uniprot Id
P25724
Target Species
Drosophila melanogaster
Target Name
NOS
Target Function
Maternal RNA-binding protein that is required for germ cells proliferation and self-renewal. Acts by forming a complex with pum and brat that regulates translation and mRNA stability. The complex binds to the Nanos Response Element (NRE), a 16 bp sequence in the hb mRNA 3'-UTR and prevents its translation. Controls posterior development. Rescuing factor for the abdominal defect of posterior group mutants. The other posterior group genes are not required for nanos function but rather play a role in localization or distribution of nanos protein.
Target Subcellular Location
Cytoplasm, Cytoplasmic ribonucleoprotein granule.
Target Protein Families
Nanos family
Target Tissue Specificity
Posterior part of the embryo. While the transcript is present throughout the embryo, nos translation is controlled by smg, and the protein is found in pole plasm and pole cells.
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