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The antibody against IGFBP1 was raised in mouse using the Recombinant Human IGFBP1 Protein as the immunogen. This antibody exists as a non-conjugated isotype IgG1, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against IGFBP1 was raised in mouse using the Recombinant Human IGFBP1 Protein as the immunogen. This antibody exists as a non-conjugated isotype IgG1, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$350.00
| Cat.No | ADC-55465A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Mouse | Target Name | IGFBP1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG1 | Storage Buffer | 15mmol/L NaN3Constituents: 0.1mol/L Nacl |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human IGFBP1 Protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P08833 |
Uniprot Id
P08833
Target Species
Human
Target Name
IGFBP1
Target Full Name
Insulin-like growth factor-binding protein 1
Target Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration.
Target Subcellular Location
Secreted.
Target Synonyms
AFBP; IBP1; PP12; IGF-BP25; hIGFBP-1; IGFBP1
Target Background
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP N-terminal domain and a thyroglobulin type-I domain. The encoded protein, mainly expressed in the liver, circulates in the plasma and binds both insulin-like growth factors (IGFs) I and II, prolonging their half-lives and altering their interaction with cell surface receptors. This protein is important in cell migration and metabolism. Low levels of this protein may be associated with impaired glucose tolerance, vascular disease and hypertension in human patients.
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