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The recombinant antibody against DEFB1 was produced using a synthesized peptide derived from Human DEFB1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, FC.
The recombinant antibody against DEFB1 was produced using a synthesized peptide derived from Human DEFB1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, FC.
$350.00
| Cat.No | ADC-56512A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | DEFB1 | Target Synonyms | BD1 HBD1, beta 1), Beta-defensin 1 (BD-1) (hBD-1) (Defensin, DEFB1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, FC | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human DEFB1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P60022 |
Uniprot Id
P60022
Target Species
Human
Target Name
DEFB1
Target Full Name
Beta-defensin 1
Target Function
Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility.
Target Subcellular Location
Secreted. Membrane.
Target Protein Families
Beta-defensin family
Target Tissue Specificity
Blood plasma. Sperm. Highly expressed in the lower head and midpiece of sperm. Significantly reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein level).
Target Synonyms
BD 1; BD-1; BD1; beta 1; Beta defensin 1; Beta-defensin 1; DEFB 1; DEFB1; DEFB1_HUMAN; DEFB101; Defensin; Defensin beta 1; Defensin beta 1 preproprotein; HBD 1; hBD-1; HBD1; MGC51822
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