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Rabbit anti-Human GTF3C4 Polyclonal Antibody

The antibody against GTF3C4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 583-822 of human GTF3C4 (NP_036336.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-01011A

The antibody against GTF3C4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 583-822 of human GTF3C4 (NP_036336.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-01011A ClonalityPolyclonal
Host SpeciesRabbitTarget NameGTF3C4
Target SynonymsKAT12; TFIII90; TFIIIC90; TFIIIC290; TF3C-delta; TFIIICDELTA; GTF3C4FormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, BT-474, Jurkat, SW620, U-251MGApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 583-822 of human GTF3C4 (NP_036336.2).Target SpeciesHuman
Uniprot IDQ9UKN8Immunogen Sequence
Background Information
  • Uniprot Id

    Q9UKN8

  • Target Species

    Human

  • Target Name

    GTF3C4

  • Target Full Name

    General transcription factor 3C polypeptide 4

  • Target Function

    Essential for RNA polymerase III to make a number of small nuclear and cytoplasmic RNAs, including 5S RNA, tRNA, and adenovirus-associated (VA) RNA of both cellular and viral origin. Has histone acetyltransferase activity (HAT) with unique specificity for free and nucleosomal H3. May cooperate with GTF3C5 in facilitating the recruitment of TFIIIB and RNA polymerase through direct interactions with BRF1, POLR3C and POLR3F. May be localized close to the A box.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    TFIIIC subunit 4 family

  • Target Synonyms

    EC 2.3.1.48; FLJ21002; General transcription factor 3C 4; General transcription factor 3C polypeptide 4; General transcription factor IIIC, polypeptide 4, 90kDa; GTF3C4; KAT12; MGC138450; OTTHUMP00000022434; TF3C delta; TF3C-delta; TF3C4_HUMAN; TFIII90; TFIIIC 90 kDa subunit; TFiiiC2 90; TFIIIC290; TFIIIC90; TFIIICdelta; Transcription factor IIIC 90 kDa subunit; Transcription factor IIIC subunit delta

  • Target Background

    Predicted to enable enzyme activator activity. Predicted to contribute to DNA binding activity. Predicted to be involved in 5S class rRNA transcription by RNA polymerase III and tRNA transcription by RNA polymerase III. Located in mitochondrion and nucleoplasm. Part of transcription factor TFIIIC complex.

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