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The antibody against VPS28 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human VPS28 (NP_057292.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against VPS28 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human VPS28 (NP_057292.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01047A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | VPS28 |
| Target Synonyms | VPS28 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat brain, 293T, A-549, HepG2, Mouse brain, Mouse liver, Mouse spleen, U-251MG | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human VPS28 (NP_057292.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UK41 | Immunogen Sequence |
Uniprot Id
Q9UK41
Target Species
Human
Target Name
VPS28
Target Full Name
Vacuolar protein sorting-associated protein 28 homolog
Target Function
Component of the ESCRT-I complex, a regulator of vesicular trafficking process.
Target Subcellular Location
Cell membrane. Late endosome membrane; Peripheral membrane protein.
Target Protein Families
VPS28 family
Target Synonyms
ESCRT-I complex subunit VPS28; H-Vps28; Vacuolar protein sorting 28; Vacuolar protein sorting 28 (yeast); Vacuolar protein sorting 28 homolog (S. cerevisiae); Vacuolar protein sorting 28 homolog; Vacuolar protein sorting-associated protein 28 homolog; VPS 28; Vps28; VPS28_HUMAN; Yeast class E protein Vps28p homolog
Target Background
This gene encodes a protein subunit of the ESCRT-I complex (endosomal complexes required for transport), which functions in the transport and sorting of proteins into subcellular vesicles. This complex can also be hijacked to facilitate the budding of enveloped viruses from the cell membrane. Alternative splicing results in multiple transcript variants encoding different isoforms.
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