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The antibody against SRP14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human SRP14 (NP_003125.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against SRP14 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human SRP14 (NP_003125.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03338A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SRP14 |
| Target Synonyms | ALURBP; SRP14 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 22Rv1, A-549, HepG2, HT-29 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-136 of human SRP14 (NP_003125.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MVLLESEQFLTELTRLFQKCRTSGSVYITLKKYDGRTKPIPKKGTVEGFEPADNKCLLRATDGKKKISTVVSSKEVNKFQMAYSNLLRANMDGLKKRDKKNKTKKTKAAAAAAAAAPAAAATAPTTAATTAATAAQ | Uniprot ID | P37108 |
Uniprot Id
P37108
Target Species
Human
Target Name
SRP14
Target Full Name
Signal recognition particle 14 kDa protein
Target Function
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
Target Subcellular Location
Cytoplasm.
Target Protein Families
SRP14 family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
18 kDa Alu RNA binding protein; 18 kDa Alu RNA-binding protein; Alu RNA-binding protein, 14-KD subunit; ALURBP; MGC14326; Signal recognition particle 14 kDa protein; signal recognition particle 14kDa (homologous Alu RNA binding protein); SRP 14; SRP14; SRP14_HUMAN
Target Background
Enables RNA binding activity. Involved in protein targeting to ER. Located in nucleus. Part of signal recognition particle, endoplasmic reticulum targeting.
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