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The antibody against PDCD2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human PDCD2 (NP_002589.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against PDCD2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human PDCD2 (NP_002589.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05156A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PDCD2 |
| Target Synonyms | RP8; ZMYND7; PDCD2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, 293T | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-344 of human PDCD2 (NP_002589.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q16342 | Immunogen Sequence |
Uniprot Id
Q16342
Target Species
Human
Target Name
PDCD2
Target Full Name
Programmed cell death protein 2
Target Function
May be a DNA-binding protein with a regulatory function. May play an important role in cell death and/or in regulation of cell proliferation.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Ubiquitous.
Target Research Area
Cell Biology
Target Synonyms
MGC12347; OTTHUMP00000017702; PDCD 2; Pdcd2; PDCD2 protein; PDCD2_HUMAN; Programmed cell death 2; Programmed cell death protein 2; RP 8; RP8; Rp8 homolog; Zinc finger MYND domain containing protein 7; Zinc finger MYND domain-containing protein 7; Zinc finger protein Rp 8; Zinc finger protein Rp-8; Zinc finger protein Rp8; ZMYND 7; ZMYND7
Target Background
This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12.
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