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The antibody against GALM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human GALM (NP_620156.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against GALM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human GALM (NP_620156.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05692A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GALM |
| Target Synonyms | GLAT; IBD1; GALAC4; BLOCK25; HEL-S-63p; GALM | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-431, HepG2, Mouse liver, OVCAR3, Rat kidney, Rat liver, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-342 of human GALM (NP_620156.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96C23 | Immunogen Sequence |
Uniprot Id
Q96C23
Target Species
Human
Target Name
GALM
Target Full Name
Galactose mutarotase
Target Function
Mutarotase that catalyzes the interconversion of beta-D-galactose and alpha-D-galactose during galactose metabolism. Beta-D-galactose is metabolized in the liver into glucose 1-phosphate, the primary metabolic fuel, by the action of four enzymes that constitute the Leloir pathway: GALM, GALK1 (galactokinase), GALT (galactose-1-phosphate uridylyltransferase) and GALE (UDP-galactose-4'-epimerase). Involved in the maintenance of the equilibrium between the beta- and alpha-anomers of galactose, therefore ensuring a sufficient supply of the alpha-anomer for GALK1. Also active on D-glucose although shows a preference for galactose over glucose.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Aldose epimerase family
Target Research Area
Metabolism
Target Synonyms
Aldose 1 epimerase; Aldose 1-epimerase; BLOCK25; Galactomutarotase; Galactose mutarotase; Galm; GALM_HUMAN; IBD1
Target Background
This gene encodes an enzyme that catalyzes the epimerization of hexose sugars such as glucose and galactose. The encoded protein is expressed in the cytoplasm and has a preference for galactose. The encoded protein may be required for normal galactose metabolism by maintaining the equilibrium of alpha and beta anomers of galactose.
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