Rabbit anti-Human TREML1 Polyclonal Antibody

The antibody against TREML1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06444A

Number

Cat.No	ADA-06444A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	TREML1
Target Synonyms	TLT1; TLT-1; PRO3438; GLTL1825; dJ238O23.3; TREML1	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse liver, Mouse lung, Rat liver	Application	ELISA, WB

Cat.No

ADA-06444A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

TREML1

Target Synonyms

TLT1; TLT-1; PRO3438; GLTL1825; dJ238O23.3; TREML1

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse liver, Mouse lung, Rat liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1).	Target Species	Human
Immunogen Sequence	QGIVGSLPEVLQAPVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQPLVSSAVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQILHRVSLNILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQDEKSIP	Uniprot ID	Q86YW5

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_835468.1).

Target Species

Human

Immunogen Sequence

QGIVGSLPEVLQAPVGSSILVQCHYRLQDVKAQKVWCRFLPEGCQPLVSSAVDRRAPAGRRTFLTDLGGGLLQVEMVTLQEEDAGEYGCMVDGARGPQILHRVSLNILPPEEEEETHKIGSLAENAFSDPAGSANPLEPSQDEKSIP

Uniprot ID

Q86YW5

Background Information

Uniprot Id

Q86YW5
Target Species

Human
Target Name

TREML1
Target Full Name

Trem-like transcript 1 protein
Target Function

Cell surface receptor that may play a role in the innate and adaptive immune response.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic vesicles in resting platelets (PubMed:15100151). Transported to the cell surface after stimulation by thrombin (PubMed:15100151). Soluble fragments can be released into the serum by proteolysis (PubMed:16505478).
Target Tissue Specificity

Detected in platelets, monocytic leukemia and in T-cell leukemia.
Target Synonyms

dJ238O23.3; GLTL1825; MGC119173; PRO3438; TLT 1; TLT-1; TLT1; TREM like transcript 1; Trem like transcript 1 protein; Trem-like transcript 1 protein; TREML 1; Treml1; Triggering receptor expressed on myeloid cells like 1; Triggering receptor expressed on myeloid cells like protein 1; Triggering receptor expressed on myeloid cells-like protein 1; TRML1_HUMAN
Target Background

This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray platelet syndrome. Alternative splicing results in multiple transcript variants

Rabbit anti-Human TREML1 Polyclonal Antibody

Specifications

Immunogen Information

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