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Rabbit anti-Human CLCC1 Polyclonal Antibody

The antibody against CLCC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 302-501 of human CLCC1 (NP_055942.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-06999A

The antibody against CLCC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 302-501 of human CLCC1 (NP_055942.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-06999A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLCC1
Target SynonymsMCLC; RP32; CLCC1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples22Rv1, Mouse spleen, U-87MGApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 302-501 of human CLCC1 (NP_055942.1).Target SpeciesHuman
Immunogen SequenceGAGKSVHVLRHIGGPESEPPQALRPRDRRRQEEIDYRPDGGAGDADFHYRGQMGPTEQGPYAKTYEGRREILRERDVDLRFQTGNKSPEVLRAFDVPDAEAREHPTVVPSHKSPVLDTKPKETGGILGEGTPKESSTESSQSAKPVSGQDTSGNTEGSPAAEKAQLKSEAAGSPDQGSTYSPARGVAGPRGQDPVSSPCGUniprot IDQ96S66
Background Information
  • Uniprot Id

    Q96S66

  • Target Species

    Human

  • Target Name

    CLCC1

  • Target Full Name

    Chloride channel CLIC-like protein 1

  • Target Function

    Seems to act as a chloride ion channel. Plays a role in retina development.

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Nucleus membrane; Multi-pass membrane protein.

  • Target Protein Families

    Chloride channel MCLC family

  • Target Tissue Specificity

    Expressed in the retina of the eye, with extensive expression in the lamina cribrosa, optic nerve, ganglion cell layer, inner nuclear layer, outer nuclear layer and retinal pigment epithelium.

  • Target Synonyms

    CLCC1; KIAA0761; MCLC; Chloride channel CLIC-like protein 1; Mid-1-related chloride channel protein 1

  • Target Background

    Predicted to enable chloride channel activity. Predicted to be involved in chloride transport. Located in endoplasmic reticulum and mitochondria-associated endoplasmic reticulum membrane. Implicated in retinitis pigmentosa 32.

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