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Rabbit anti-Human LIN9 Polyclonal Antibody

The antibody against LIN9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human LIN9 (NP_775106.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-07156A

The antibody against LIN9 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human LIN9 (NP_775106.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-07156A ClonalityPolyclonal
Host SpeciesRabbitTarget NameLIN9
Target SynonymsTGS; BARA; TGS1; TGS2; Lin-9; BARPsv; LIN9FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 350-470 of human LIN9 (NP_775106.2).Target SpeciesHuman
Immunogen SequenceTLGGFPVEFLIQVTRLSKILMIKKEHIKKLREMNTEAEKLKSYSMPISIEFQRRYATIVLELEQLNKDLNKVLHKVQQYCYELAPDQGLQPADQPTDMRRRCEEEAQEIVRHANSSTGQPCUniprot IDQ5TKA1
Background Information
  • Uniprot Id

    Q5TKA1

  • Target Species

    Human

  • Target Name

    LIN9

  • Target Full Name

    Protein lin-9 homolog

  • Target Function

    Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.

  • Target Subcellular Location

    Nucleus, nucleoplasm. Note=Found in perinucleolar structures. Associated with chromatin.

  • Target Protein Families

    Lin-9 family

  • Target Tissue Specificity

    Expressed in thymus and testis.

  • Target Synonyms

    BARA; Beta subunit-associated regulator of apoptosis; Beta-subunit associated regulator of apoptosis; hLin-9; huLin-9; lin-9 ; lin9; LIN9_HUMAN; pRB-associated protein; Protein lin-9 homolog; TGS; TUDOR gene similar protein; Type I interferon receptor beta chain-associated protein

  • Target Background

    This gene encodes a tumor suppressor protein that inhibits DNA synthesis and oncogenic transformation through association with the retinoblastoma 1 protein. The encoded protein also interacts with a complex of other cell cycle regulators to repress cell cycle-dependent gene expression in non-dividing cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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