Rabbit anti-Human NCEH1 Polyclonal Antibody

The antibody against NCEH1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 90-440 of human NCEH1 (NP_065843.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-10522A

Number

Cat.No	ADA-10522A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NCEH1
Target Synonyms	NCEH; AADACL1; NCEH1	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	BxPC-3, PC-3	Application	ELISA, WB

Cat.No

ADA-10522A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NCEH1

Target Synonyms

NCEH; AADACL1; NCEH1

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

BxPC-3, PC-3

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 90-440 of human NCEH1 (NP_065843.3).	Target Species	Human
Uniprot ID	Q6PIU2	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 90-440 of human NCEH1 (NP_065843.3).

Target Species

Human

Uniprot ID

Q6PIU2

Immunogen Sequence

Background Information

Uniprot Id

Q6PIU2
Target Species

Human
Target Name

NCEH1
Target Full Name

Neutral cholesterol ester hydrolase 1
Target Function

Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.
Target Subcellular Location

Cell membrane; Single-pass type II membrane protein. Microsome.
Target Protein Families

'GDXG' lipolytic enzyme family
Target Tissue Specificity

Expressed in monocyte-derived macrophages. Up-regulated in invasive melanoma and breast carcinoma cell lines.
Target Synonyms

Arylacetamide deacetylase like 1; Arylacetamide deacetylase-like 1; NCEH; Nceh1; NCEH1_HUMAN; Neutral cholesterol ester hydrolase 1; Neutral cholesterol ester hydrolase
Target Background

Predicted to enable hydrolase activity. Predicted to be involved in ether lipid metabolic process. Predicted to act upstream of or within SMAD protein signal transduction; protein dephosphorylation; and xenobiotic metabolic process. Located in membrane.

Rabbit anti-Human NCEH1 Polyclonal Antibody

Specifications

Immunogen Information

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