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The antibody against Siglec-15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-263 of human Siglec-15 (NP_998767.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against Siglec-15 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-263 of human Siglec-15 (NP_998767.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-10580A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | Siglec-15 |
| Target Synonyms | CD33L3; HsT1361; SIGLEC-15; Siglec-15 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, HUVEC | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 20-263 of human Siglec-15 (NP_998767.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q6ZMC9 | Immunogen Sequence |
Uniprot Id
Q6ZMC9
Target Species
Human
Target Name
SIGLEC15
Target Full Name
Sialic acid-binding Ig-like lectin 15
Target Function
Binds sialylated glycoproteins.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.
Target Protein Families
Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family
Target Tissue Specificity
Expressed in macrophage and/or dendritic cells of spleen and lymph nodes.
Target Research Area
Others
Target Synonyms
CD33 antigen-like 3; CD33 molecule-like 3; CD33L3; HsT1361; Sialic acid-binding Ig-like lectin 15; SIG15_HUMAN; Siglec-15; SIGLEC15
Target Background
Predicted to be involved in regulation of actin cytoskeleton organization; regulation of bone resorption; and regulation of osteoclast development. Predicted to be integral component of membrane. Predicted to be part of protein-containing complex. Predicted to be active in plasma membrane.
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