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The recombinant antibody against ALAS1 was produced using a synthesized peptide derived from human Alas1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
The recombinant antibody against ALAS1 was produced using a synthesized peptide derived from human Alas1 as the immunogen. This antibody exists as a non-conjugated isotype Rabbit IgG, Affinity-chromatography purified. This antibody has been validated on ELISA, WB.
$350.00
Western Blot | Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, Raji whole cell lysate, PC-3 whole cell lysate, A549 whole cell lysate, MCF-7 whole cell lysate | All lanes: ALAS1 antibody at 1:1500 | Secondary | Goat polyclonal to rabbit IgG at 1/50000 dilution | Predicted band size: 71, 13 kDa | Observed band size: 71 kDa
| Cat.No | ADC-57093A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | ALAS1 | Target Synonyms | 5-aminolevulinate synthase, ALAS1, ALAS3 ALASH, mitochondrial (ALAS-H) (EC 2.3.1.37) (5-aminolevulinic acid synthase 1) (Delta-ALA synthase 1) (Delta-aminolevulinate synthase 1), nonspecific |
| Form | Liquid | Species Reactivity | Human |
| Isotype | Rabbit IgG | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from human Alas1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P13196 |
Uniprot Id
P13196
Target Species
Human
Target Name
ALAS1
Target Full Name
5-aminolevulinate synthase, non-specific, mitochondrial
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-II pyridoxal-phosphate-dependent aminotransferase family
Target Synonyms
5 aminolevulinate synthase ; 5 aminolevulinate synthase nonspecific mitochondrial; 5 aminolevulinic acid synthase; 5-aminolevulinate synthase; 5-aminolevulinic acid synthase 1; Alas 1; ALAS 3; ALAS; ALAS H; ALAS HOUSEKEEPING TYPE; ALAS N; ALAS-H; alaS1; ALAS3; ALASH; Aminolevulinate delta synthase 1; Aminolevulinic acid synthase 1 ; Delta ALA synthetase; Delta aminolevulinate synthase; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1; HEM1_HUMAN; MIG 4; MIG4; Migration inducing protein 4; mitochondrial; nonspecific
Target Background
This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.
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