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The antibody against ADGRB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 70-280 of human ADGRB3 (NP_001695.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ADGRB3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 70-280 of human ADGRB3 (NP_001695.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02102A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADGRB3 |
| Target Synonyms | BAI3; ADGRB3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 70-280 of human ADGRB3 (NP_001695.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O60242 | Immunogen Sequence |
Uniprot Id
O60242
Target Species
Human
Target Name
ADGRB3
Target Full Name
Adhesion G protein-coupled receptor B3
Target Function
Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity. Promotes myoblast fusion through ELMO/DOCK1.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 2 family, Adhesion G-protein coupled receptor (ADGR) subfamily
Target Tissue Specificity
Strongly expressed in brain. Also detected in heart. Reduced expression in some glioblastoma cell lines.
Target Synonyms
BAI3; BAI3_HUMAN; Brain-specific angiogenesis inhibitor 3; dJ91B17.1 (brain specific angiogenesis inhibitor 3); KIAA0550
Target Background
This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis.
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