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Rabbit anti-Human AGPAT4 Polyclonal Antibody

The antibody against AGPAT4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 270-378 of human AGPAT4(NP_064518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08320A

The antibody against AGPAT4 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 270-378 of human AGPAT4(NP_064518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-08320A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAGPAT4
Target SynonymsLPAAT4; LPLAT4; 1-AGPAT4; dJ473J16.2; LPAAT-delta; AGPAT4FormLiquid
Species ReactivityMouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 270-378 of human AGPAT4(NP_064518.1).Target SpeciesHuman
Immunogen SequenceCSAWLHKLYQEKDAFQEEYYRTGTFPETPMVPPRRPWTLVNWLFWASLVLYPFFQFLVSMIRSGSSLTLASFILVFFVASVGVRWMIGVTEIDKGSAYGNSDSKQKLNDUniprot IDQ9NRZ5
Background Information
  • Uniprot Id

    Q9NRZ5

  • Target Species

    Human

  • Target Name

    AGPAT4

  • Target Full Name

    1-acyl-sn-glycerol-3-phosphate acyltransferase delta

  • Target Function

    Converts 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Exhibits high acyl-CoA specificity for polyunsaturated fatty acyl-CoA, especially docosahexaenoyl-CoA (22:6-CoA, DHA-CoA).

  • Target Subcellular Location

    Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    1-acyl-sn-glycerol-3-phosphate acyltransferase family

  • Target Tissue Specificity

    Widely expressed with highest levels in skeletal muscle, followed by heart, liver, prostate and thymus.

  • Target Synonyms

    AGPAT4; UNQ499/PRO1016; 1-acyl-sn-glycerol-3-phosphate acyltransferase delta; 1-acylglycerol-3-phosphate O-acyltransferase 4; 1-AGP acyltransferase 4; 1-AGPAT 4; Lysophosphatidic acid acyltransferase delta; LPAAT-delta

  • Target Background

    This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. This integral membrane protein converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis.

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