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The antibody against ARFGAP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 242-521 of human ARFGAP2 (NP_115765.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against ARFGAP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 242-521 of human ARFGAP2 (NP_115765.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-07097A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ARFGAP2 |
| Target Synonyms | IRZ; ZFP289; ZNF289; NBLA10535; ARFGAP2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse kidney, Rat lung, Rat testis, THP-1 | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 242-521 of human ARFGAP2 (NP_115765.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8N6H7 | Immunogen Sequence |
Uniprot Id
Q8N6H7
Target Species
Human
Target Name
ARFGAP2
Target Full Name
ADP-ribosylation factor GTPase-activating protein 2
Target Function
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Target Subcellular Location
Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Target Synonyms
ADP-ribosylation factor GTPase-activating protein 2; ARF GAP 2; ARFG2_HUMAN; ARFGAP2; FLJ14576; FLJ26000; GTPase activating protein ZNF289; GTPase-activating protein ZNF289; IRZ; Nbla10535 ; Zfp289; Zinc finger protein 289; Zinc finger protein 289 ID1 regulated; ZNF289
Target Background
Predicted to enable GTPase activator activity. Predicted to be involved in COPI coating of Golgi vesicle. Located in Golgi apparatus; cytosol; and plasma membrane.
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