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The antibody against ASAP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human ASAP2 (NP_001128663) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ASAP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human ASAP2 (NP_001128663) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06948A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ASAP2 |
| Target Synonyms | PAP; PAG3; AMAP2; DDEF2; SHAG1; CENTB3; Pap-alpha; ASAP2 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human ASAP2 (NP_001128663). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MPDQISVSEFVAETHEDYKAPTASSFTTRTAQCRNTVAAIEEALDVDRMVLYKMKKSVKAINSSGLAHVENEEQYTQALEKFGGNCVCRDDPDLGSAFLKFSVFTKELTALFKNLIQNMN | Uniprot ID | O43150 |
Uniprot Id
O43150
Target Species
Human
Target Name
ASAP2
Target Full Name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2
Target Function
Activates the small GTPases ARF1, ARF5 and ARF6. Regulates the formation of post-Golgi vesicles and modulates constitutive secretion. Modulates phagocytosis mediated by Fc gamma receptor and ARF6. Modulates PXN recruitment to focal contacts and cell migration.
Target Subcellular Location
Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Colocalizes with F-actin and ARF6 in phagocytic cups.
Target Tissue Specificity
Detected in heart, brain, placenta, kidney, monocytes and pancreas.
Target Synonyms
AMAP 2; AMAP2; ANK repeat and PH domain-containing protein 2; Arf-GAP with SH3 domain; ArfGAP with SH3 domain; ankyrin repeat and PH domain 2; ASAP2; ASAP2_HUMAN; centaurin; beta 3; CENTB3; DDEF 2; DDEF2; Development and differentiation enhancing factor 2; Development and differentiation-enhancing factor 2; FLJ42910; KIAA0400; PAG 3; PAG3; Pap alpha; PAP; Paxillin associated protein with ARFGAP activity 3; Paxillin-associated protein with ARF GAP activity 3; Pyk2 C terminus associated protein; Pyk2 C-terminus-associated protein; SHAG 1; SHAG1
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