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The antibody against ATMIN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human ATMIN (NP_056066.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against ATMIN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human ATMIN (NP_056066.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-02599A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ATMIN |
| Target Synonyms | ASCIZ; ZNF822; ATMIN | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, MCF7, Mouse testis | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 160-360 of human ATMIN (NP_056066.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43313 | Immunogen Sequence |
Uniprot Id
O43313
Target Species
Human
Target Name
ATMIN
Target Full Name
ATM interactor
Target Function
Transcription factor. Plays a crucial role in cell survival and RAD51 foci formation in response to methylating DNA damage. Involved in regulating the activity of ATM in the absence of DNA damage. May play a role in stabilizing ATM. Binds to the DYNLL1 promoter and activates its transcription.
Target Subcellular Location
Nucleus. Note=Nuclear, in discrete foci during G1 phase.
Target Tissue Specificity
Ubiquitously expressed in normal tissues and cancer cell lines with highest levels in placenta and skeletal muscle.
Target Synonyms
ASCIZ; ATM INteracting protein; ATM interactor; ATM substrate CHK2-interacting zinc finger protein; ATM/ATR substrate CHEK2 interacting zinc finger protein; ATM/ATR Substrate Chk2 Interacting Zn++ finger protein; ATM/ATR substrate Chk2 interacting Zn2+ finger protein; ATM/ATR-substrate CHK2-interacting zinc finger protein; ATMIN; ATMIN_HUMAN; DKFZp779K1455; FLJ76795; KIAA0431; Zinc finger protein 822; ZNF 822; ZNF822
Target Background
Enables dynein complex binding activity. Involved in positive regulation of transcription, DNA-templated. Located in nuclear body.
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