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The antibody against B4GALNT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 26-240 of human B4GALNT1 (NP_001263398.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against B4GALNT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 26-240 of human B4GALNT1 (NP_001263398.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04040A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | B4GALNT1 |
| Target Synonyms | GALGT; SPG26; GALNACT; GalNAc-T; B4GALNT1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A375, MCF7, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 26-240 of human B4GALNT1 (NP_001263398.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q00973 | Immunogen Sequence |
Uniprot Id
Q00973
Target Species
Human
Target Name
B4GALNT1
Target Full Name
Beta-1,4 N-acetylgalactosaminyltransferase 1
Target Function
Involved in the biosynthesis of gangliosides GM2, GD2, GT2 and GA2 from GM3, GD3, GT3 and GA3, respectively.
Target Involvement
Spastic paraplegia 26, autosomal recessive (SPG26)
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 2 family
Target Synonyms
GALGT; SPG26; GALNACT; GalNAc-T; B4GALNT1
Target Background
GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. GalNAc-T catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1, 4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively. Three transcript variants encoding different isoforms have been found for this gene.
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