Rabbit anti-Human BCAT1 Polyclonal Antibody

The antibody against BCAT1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-00336A

Number

Cat.No	ADA-00336A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	BCAT1
Target Synonyms	BCT1; PP18; BCATC; ECA39; MECA39; PNAS121; BCAT1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, Mouse brain, Neuro-2a, Raji, SH-SY5Y	Application	ELISA, WB, IF/ICC

Cat.No

ADA-00336A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

BCAT1

Target Synonyms

BCT1; PP18; BCATC; ECA39; MECA39; PNAS121; BCAT1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, Mouse brain, Neuro-2a, Raji, SH-SY5Y

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2).	Target Species	Human
Immunogen Sequence	EVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPV	Uniprot ID	P54687

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human BCAT1 (NP_005495.2).

Target Species

Human

Immunogen Sequence

EVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTVEWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRMYRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTKALLFVLLSPV

Uniprot ID

P54687

Background Information

Uniprot Id

P54687
Target Species

Human
Target Name

BCAT1
Target Full Name

Branched-chain-amino-acid aminotransferase, cytosolic
Target Function

Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Target Subcellular Location

Cytoplasm.
Target Protein Families

Class-IV pyridoxal-phosphate-dependent aminotransferase family
Target Tissue Specificity

During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitt's lymphoma.
Target Synonyms

BCAT ; BCAT(c); Bcat1; BCAT1_HUMAN; BCT1 ; Branched chain amino acid aminotransferase; cytosolic ; branched chain amino-acid transaminase 1; cytosolic; branched chain aminotransferase 1; branched chain aminotransferase 1; cytosolic; Branched-chain-amino-acid aminotransferase; cytosolic; DKFZp686E12175 ; EC 2.6.1.42; ECA39 ; MECA39 ; placental protein 18; PNAS 121 ; PP18; Protein ECA39
Target Background

This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described.

Rabbit anti-Human BCAT1 Polyclonal Antibody

Specifications

Immunogen Information

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