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The antibody against BTAF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1600-1849 of human BTAF1 (NP_003963.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ChIP, ELISA.
The antibody against BTAF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1600-1849 of human BTAF1 (NP_003963.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IP, ChIP, ELISA.
| Cat.No | ADA-03663A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | BTAF1 |
| Target Synonyms | MOT1; TAF172; TAFII170; TAF(II)170; BTAF1 | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HepG2, MCF7, Rat testis | Application | ELISA, WB, ChIP, IP |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1600-1849 of human BTAF1 (NP_003963.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O14981 | Immunogen Sequence |
Uniprot Id
O14981
Target Species
Human
Target Name
BTAF1
Target Full Name
TATA-binding protein-associated factor 172
Target Function
Regulates transcription in association with TATA binding protein (TBP). Removes TBP from the TATA box in an ATP-dependent manner.
Target Subcellular Location
Nucleus.
Target Protein Families
SNF2/RAD54 helicase family
Target Synonyms
ATP dependent helicase BTAF1; ATP-dependent helicase BTAF1; B-TFIID transcription factor associated 170 kDa subunit ; B-TFIID transcription factor associated, 170kDa (Mot1 homolog, S. cerevisiae); B-TFIID transcription factor-associated 170 kDa subunit; BTAF 1 RNA polymerase II; BTAF1; BTAF1 RNA polymerase II B TFIID transcription factor associated 170kDa; BTAF1_HUMAN; MOT 1; MOT1; MOT1 Yeast homolog of; TAF 172; TAF II 170; TAF(II)170; TAF-172; TAF172; TAFII170; TATA binding protein associated factor 172; TATA-binding protein-associated factor 172; TBP associated factor 172; TBP-associated factor 172
Target Background
This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters.
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