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The antibody against C11orf30 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1153-1322 of human C11orf30 (NP_064578.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against C11orf30 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1153-1322 of human C11orf30 (NP_064578.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
Immunofluorescence analysis of HeLa cells using C11orf30 antibody. Blue: DAPI for nuclear staining.
| Cat.No | ADA-06137A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C11orf30 |
| Target Synonyms | GL002; C11orf30 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1153-1322 of human C11orf30 (NP_064578.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | SLMEAQIDTNVEHMIVDPPKKALATSMLTGEAGSLPSTHMVVAGMANSTPQQQKCRESCSSPSTVGSSLTTRKIDPPAVPATGQFMRIQNVGQKKAEESPAEIIIQAIPQYAIPCHSSSNVVVEPSGLLELNNFTSQQLDDEETAMEQDIDSSTEDGTEPSPSQSSAERS | Uniprot ID | Q7Z589 |
Uniprot Id
Q7Z589
Target Species
Human
Target Name
EMSY
Target Full Name
BRCA2-interacting transcriptional repressor EMSY
Target Function
Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. Mediates ligand-dependent transcriptional activation by nuclear hormone receptors.
Target Subcellular Location
Nucleus. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.
Target Synonyms
C11orf30; Chromosome 11 open reading frame 30; Emsy; EMSY protein; EMSY_HUMAN; FLJ90741; GL002; Protein EMSY
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