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The antibody against CA7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human CA7 (NP_005173.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CA7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human CA7 (NP_005173.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05697A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CA7 |
| Target Synonyms | CAVII; CA-VII; CA7 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Rat brain, 293T, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-264 of human CA7 (NP_005173.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P43166 | Immunogen Sequence |
Uniprot Id
P43166
Target Species
Human
Target Name
CA7
Target Full Name
Carbonic anhydrase 7
Target Function
Reversible hydration of carbon dioxide.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Alpha-carbonic anhydrase family
Target Synonyms
CA 7; CA VII; CA-VII; Ca7; CAH7_HUMAN; Carbonate dehydratase VII; Carbonic anhydrase 7; Carbonic anhydrase VII; Carbonic dehydratase VII; CAVII; EC=4.2.1.1
Target Background
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms.
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