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The antibody against CD109 was raised in Rabbit using the recombinant protein of human CD109 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CD109 was raised in Rabbit using the recombinant protein of human CD109 as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-13524A | Clonality | Monoclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CD109 |
| Target Synonyms | CD109; CPAMD7; p180; r150; CD109 antigen | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | A-549 | Application | ELISA, WB |
| Immunogen Description | Recombinant protein of human CD109. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6YHK3 |
Uniprot Id
Q6YHK3
Target Species
Human
Target Name
CD109
Target Full Name
CD109 antigen
Target Function
Modulates negatively TGFB1 signaling in keratinocytes.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor.
Target Protein Families
Protease inhibitor I39 (alpha-2-macroglobulin) family
Target Tissue Specificity
Widely expressed with high level in uterus, aorta, heart, lung, trachea, placenta and in fetal heart, kidney, liver, spleen and lung. Expressed by CD34(+) acute myeloid leukemia cell lines, T-cell lines, activated T-lymphoblasts, endothelial cells and act
Target Synonyms
150 KDa TGF beta 1 binding protein; 150 KDa TGF-beta-1-binding protein; 7D1; 8A3; Activated T cell marker CD109; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7; CD 109; CD109; CD109 antigen; CD109_HUMAN; CPAMD7; DKFZp762L1111; E123; FLJ38569; FLJ41966; Gov system alloantigens on platelets; p180; Platelet specific Gov antigen; Platelet-specific Gov antigen; r150; RP11 525G3.1
Target Background
This gene encodes a glycosyl phosphatidylinositol (GPI)-linked glycoprotein that localizes to the surface of platelets, activated T-cells, and endothelial cells. The protein binds to and negatively regulates signalling by transforming growth factor beta (TGF-beta). Multiple transcript variants encoding different isoforms have been found for this gene.
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