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Rabbit anti-Human CD73/NT5E Polyclonal Antibody

The antibody against CD73/NT5E was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 32-264 of human CD73/NT5E (NP_002517.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-04106A

The antibody against CD73/NT5E was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 32-264 of human CD73/NT5E (NP_002517.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-04106A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCD73/NT5E
Target SynonymsNT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA; CD73/NT5EFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse lung, Rat liverApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 32-264 of human CD73/NT5E (NP_002517.1).Target SpeciesHuman
Uniprot IDP21589Immunogen Sequence
Background Information
  • Uniprot Id

    P21589

  • Target Species

    Human

  • Target Name

    NT5E

  • Target Full Name

    5'-nucleotidase

  • Target Function

    Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities.

  • Target Involvement

    Calcification of joints and arteries (CALJA)

  • Target Subcellular Location

    Cell membrane; Lipid-anchor, GPI-anchor.

  • Target Protein Families

    5'-nucleotidase family

  • Target Synonyms

    NT; eN; NT5; NTE; eNT; CD73; E5NT; CALJA; CD73/NT5E

  • Target Background

    The protein encoded by this gene is a plasma membrane protein that catalyzes the conversion of extracellular nucleotides to membrane-permeable nucleosides. The encoded protein is used as a determinant of lymphocyte differentiation. Defects in this gene can lead to the calcification of joints and arteries. Two transcript variants encoding different isoforms have been found for this gene.

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