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The antibody against CEP83 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 34-260 of human CEP83 (NP_057206.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CEP83 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 34-260 of human CEP83 (NP_057206.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01279A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CEP83 |
| Target Synonyms | CCDC41; NPHP18; NY-REN-58; CEP83 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HT-29, Mouse lung, Mouse spleen, Mouse thymus | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 34-260 of human CEP83 (NP_057206.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9Y592 | Immunogen Sequence |
Uniprot Id
Q9Y592
Target Species
Human
Target Name
CEP83
Target Full Name
Centrosomal protein of 83 kDa
Target Function
Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly.
Target Involvement
Nephronophthisis 18 (NPHP18)
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Localizes specifically to the distal appendage region of the centriole, which anchors the mother centriole to the plasma membrane. Localizes to centrioles at all stages of the cell cycle, including mitosis.
Target Protein Families
CEP83 family
Target Research Area
Cell Biology
Target Synonyms
CEP83; CCDC41Centrosomal protein of 83 kDa; Cep83; Coiled-coil domain-containing protein 41; Renal carcinoma antigen NY-REN-58
Target Background
The protein encoded by this gene is a centriolar protein involved in primary cilium assembly. Defects in this gene have been associated with infantile nephronophthisis and intellectual disability.
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