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The antibody against CGA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-116 of human CGA (NP_000726.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CGA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 25-116 of human CGA (NP_000726.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-09283A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CGA |
| Target Synonyms | HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; CG-ALPHA; CGA | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | MCF7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 25-116 of human CGA (NP_000726.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | APDVQDCPECTLQENPFFSQPGAPILQCMGCCFSRAYPTPLRSKKTMLVQKNVTSESTCCVAKSYNRVTVMGGFKVENHTACHCSTCYYHKS | Uniprot ID | P01215 |
Uniprot Id
P01215
Target Species
Human
Target Name
CGA
Target Full Name
Glycoprotein hormones alpha chain
Target Function
Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
Target Subcellular Location
Secreted.
Target Protein Families
Glycoprotein hormones subunit alpha family
Target Synonyms
HCG; LHA; FSHA; GPA1; GPHa; TSHA; GPHA1; CG-ALPHA; CGA
Target Background
The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene.
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