Rabbit anti-Human CLIC1 Polyclonal Antibody

The antibody against CLIC1 was raised in Rabbit using the recombinant Protein corresponding to a sequence within amino acids 42-241 of human CLIC1(NP_001279.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, IP, ELISA.

ADA-08125A

Number

Cat.No	ADA-08125A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CLIC1
Target Synonyms	G6; CL1C1; NCC27; CLCNL1; [KD Validated] CLIC1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, MCF7	Application	ELISA, WB, IF/ICC, IP

Cat.No

ADA-08125A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CLIC1

Target Synonyms

G6; CL1C1; NCC27; CLCNL1; [KD Validated] CLIC1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, MCF7

Application

ELISA, WB, IF/ICC, IP

Immunogen Description	Recombinant Protein corresponding to a sequence within amino acids 42-241 of human CLIC1(NP_001279.2).	Target Species	Human
Immunogen Sequence	NVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK	Uniprot ID	O00299

Immunogen Description

Recombinant Protein corresponding to a sequence within amino acids 42-241 of human CLIC1(NP_001279.2).

Target Species

Human

Immunogen Sequence

NVTTVDTKRRTETVQKLCPGGQLPFLLYGTEVHTDTNKIEEFLEAVLCPPRYPKLAALNPESNTAGLDIFAKFSAYIKNSNPALNDNLEKGLLKALKVLDNYLTSPLPEEVDETSAEDEGVSQRKFLDGNELTLADCNLLPKLHIVQVVCKKYRGFTIPEAFRGVHRYLSNAYAREEFASTCPDDEEIELAYEQVAKALK

Uniprot ID

O00299

Background Information

Uniprot Id

O00299
Target Species

Human
Target Name

CLIC1
Target Full Name

Chloride intracellular channel protein 1
Target Function

Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.
Target Subcellular Location

Nucleus. Nucleus membrane; Single-pass membrane protein. Cytoplasm. Cell membrane; Single-pass membrane protein.
Target Protein Families

Chloride channel CLIC family
Target Tissue Specificity

Expression is prominent in heart, placenta, liver, kidney and pancreas.
Target Synonyms

CLIC1; G6; NCC27; Chloride intracellular channel protein 1; Chloride channel ABP; Nuclear chloride ion channel 27; Regulatory nuclear chloride ion channel protein; hRNCC
Target Background

Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity.

Rabbit anti-Human CLIC1 Polyclonal Antibody

Specifications

Immunogen Information

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