Rabbit anti-Human CPLX3 Polyclonal Antibody

The antibody against CPLX3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 59-158 of human CPLX3 (NP_001025176.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06106A

Number

Cat.No	ADA-06106A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CPLX3
Target Synonyms	CPXIII; CPX-III; Nbla11589; CPLX3	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Mouse brain, Mouse eye	Application	ELISA, WB

Cat.No

ADA-06106A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CPLX3

Target Synonyms

CPXIII; CPX-III; Nbla11589; CPLX3

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Mouse brain, Mouse eye

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 59-158 of human CPLX3 (NP_001025176.1).	Target Species	Human
Immunogen Sequence	DAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKDKAQATLGDLKQSAEKCHVM	Uniprot ID	Q8WVH0

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 59-158 of human CPLX3 (NP_001025176.1).

Target Species

Human

Immunogen Sequence

DAQFTQRKAERATLRSHFRDKYRLPKNETDESQIQMAGGDVELPRELAKMIEEDTEEEEEKASVLGQLASLPGLNLGSLKDKAQATLGDLKQSAEKCHVM

Uniprot ID

Q8WVH0

Background Information

Uniprot Id

Q8WVH0
Target Species

Human
Target Name

CPLX3
Target Full Name

Complexin-3
Target Function

Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release.
Target Subcellular Location

Cell junction, synapse. Cell membrane; Lipid-anchor.
Target Protein Families

Complexin/synaphin family
Target Synonyms

CPLX3; Nbla11589Complexin-3; Complexin III; CPX III
Target Background

Predicted to enable SNARE binding activity. Predicted to be involved in regulation of neurotransmitter secretion and synaptic vesicle exocytosis. Predicted to be located in plasma membrane and synapse. Predicted to be part of SNARE complex. Predicted to be active in photoreceptor ribbon synapse and terminal bouton. Predicted to be anchored component of presynaptic active zone membrane and anchored component of synaptic vesicle membrane.

Rabbit anti-Human CPLX3 Polyclonal Antibody

Specifications

Immunogen Information

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