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Rabbit anti-Human DHRS3 Polyclonal Antibody

The antibody against DHRS3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human DHRS3 (NP_004744.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00673A

The antibody against DHRS3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human DHRS3 (NP_004744.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-00673A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDHRS3
Target SynonymsSDR1; RDH17; Rsdr1; DD83.1; SDR16C1; retSDR1; DHRS3FormLiquid
Species ReactivityMouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse lung, Rat kidneyApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human DHRS3 (NP_004744.2).Target SpeciesHuman
Immunogen SequencePAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGUniprot IDO75911
Background Information
  • Uniprot Id

    O75911

  • Target Species

    Human

  • Target Name

    DHRS3

  • Target Full Name

    Short-chain dehydrogenase/reductase 3

  • Target Function

    Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.

  • Target Subcellular Location

    Membrane; Multi-pass membrane protein.

  • Target Protein Families

    Short-chain dehydrogenases/reductases (SDR) family

  • Target Tissue Specificity

    Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retin

  • Target Synonyms

    DHRS3; RDH17; SDR16C1; UNQ2424/PRO4983; Short-chain dehydrogenase/reductase 3; DD83.1; Retinal short-chain dehydrogenase/reductase 1; retSDR1; Retinol dehydrogenase 17; Short chain dehydrogenase/reductase family 16C member 1

  • Target Background

    Predicted to enable NAD-retinol dehydrogenase activity. Predicted to be involved in regulation of retinoic acid receptor signaling pathway and retinoid metabolic process. Predicted to act upstream of or within several processes, including animal organ morphogenesis; negative regulation of retinoic acid receptor signaling pathway; and regulation of ossification. Predicted to be located in endoplasmic reticulum membrane and photoreceptor outer segment membrane. Predicted to be active in lipid droplet.

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