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The antibody against DHRS3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human DHRS3 (NP_004744.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DHRS3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human DHRS3 (NP_004744.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-00673A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DHRS3 |
| Target Synonyms | SDR1; RDH17; Rsdr1; DD83.1; SDR16C1; retSDR1; DHRS3 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse lung, Rat kidney | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 30-150 of human DHRS3 (NP_004744.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | PAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLG | Uniprot ID | O75911 |
Uniprot Id
O75911
Target Species
Human
Target Name
DHRS3
Target Full Name
Short-chain dehydrogenase/reductase 3
Target Function
Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Protein Families
Short-chain dehydrogenases/reductases (SDR) family
Target Tissue Specificity
Widely expressed with highest levels found in heart, placenta, lung, liver, kidney, pancreas, thyroid, testis, stomach, trachea and spinal cord. Lower levels found in skeletal muscle, intestine and lymph node. No expression detected in brain. In the retin
Target Synonyms
DHRS3; RDH17; SDR16C1; UNQ2424/PRO4983; Short-chain dehydrogenase/reductase 3; DD83.1; Retinal short-chain dehydrogenase/reductase 1; retSDR1; Retinol dehydrogenase 17; Short chain dehydrogenase/reductase family 16C member 1
Target Background
Predicted to enable NAD-retinol dehydrogenase activity. Predicted to be involved in regulation of retinoic acid receptor signaling pathway and retinoid metabolic process. Predicted to act upstream of or within several processes, including animal organ morphogenesis; negative regulation of retinoic acid receptor signaling pathway; and regulation of ossification. Predicted to be located in endoplasmic reticulum membrane and photoreceptor outer segment membrane. Predicted to be active in lipid droplet.
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