Rabbit anti-Human DPT Polyclonal Antibody

The antibody against DPT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human DPT (NP_001928.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08951A

Number

Cat.No	ADA-08951A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	DPT
Target Synonyms	TRAMP; DPT	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse uterus	Application	ELISA, WB

Cat.No

ADA-08951A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

DPT

Target Synonyms

TRAMP; DPT

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse uterus

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human DPT (NP_001928.2).	Target Species	Human
Immunogen Sequence	QYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTEYDCEFANV	Uniprot ID	Q07507

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 19-201 of human DPT (NP_001928.2).

Target Species

Human

Immunogen Sequence

QYGDYGYPYQQYHDYSDDGWVNLNRQGFSYQCPQGQVIVAVRSIFSKKEGSDRQWNYACMPTPQSLGEPTECWWEEINRAGMEWYQTCSNNGLVAGFQSRYFESVLDREWQFYCCRYSKRCPYSCWLTTEYPGHYGEEMDMISYNYDYYIRGATTTFSAVERDRQWKFIMCRMTEYDCEFANV

Uniprot ID

Q07507

Background Information

Uniprot Id

Q07507
Target Species

Human
Target Name

DPT
Target Full Name

Dermatopontin
Target Function

Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation.
Target Subcellular Location

Secreted, extracellular space, extracellular matrix.
Target Protein Families

Dermatopontin family
Target Tissue Specificity

Expressed in fibroblasts, heart, skeletal muscle, brain and pancreas. Expressed at an intermediate level in lung and kidney, and at a low level in liver and placenta. Expressed at a lower level in fibroblasts from hypertrophic scar lesional skin and in fi
Target Synonyms

TRAMP; DPT
Target Background

Dermatopontin is an extracellular matrix protein with possible functions in cell-matrix interactions and matrix assembly. The protein is found in various tissues and many of its tyrosine residues are sulphated. Dermatopontin is postulated to modify the behavior of TGF-beta through interaction with decorin.

Rabbit anti-Human DPT Polyclonal Antibody

Specifications

Immunogen Information

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