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Rabbit anti-Human DYNC1I1 Polyclonal Antibody

The antibody against DYNC1I1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DYNC1I1 (NP_001129028.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-04053A

The antibody against DYNC1I1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DYNC1I1 (NP_001129028.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-04053A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDYNC1I1
Target SynonymsDNCI1; DNCIC1; DYNC1I1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, Rat brain, Jurkat, Mouse brain, Mouse skeletal muscle, Mouse testis, Rat testis, SH-SY5YApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human DYNC1I1 (NP_001129028.1).Target SpeciesHuman
Uniprot IDO14576Immunogen Sequence
Background Information
  • Uniprot Id

    O14576

  • Target Species

    Human

  • Target Name

    DYNC1I1

  • Target Full Name

    Cytoplasmic dynein 1 intermediate chain 1

  • Target Function

    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.

  • Target Subcellular Location

    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.

  • Target Protein Families

    Dynein intermediate chain family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    Cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein intermediate chain 1; cytosolic; DC1I1_HUMAN; DH IC 1; DH IC-1; DH IC1; DNCI1; DNCIC1; Dync1i1; Dynein cytoplasmic 1 intermediate chain 1; Dynein intermediate chain 1; Dynein intermediate chain 1; cytosolic; Dynein; cytoplasmic; intermediate polypeptide 1

  • Target Background

    Enables spectrin binding activity. Involved in vesicle transport along microtubule. Located in several cellular components, including kinetochore; recycling endosome; and spindle pole.

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