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Rabbit anti-Human DYRK4 Polyclonal Antibody

The antibody against DYRK4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human DYRK4 (NP_003836.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00265A

The antibody against DYRK4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human DYRK4 (NP_003836.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-00265A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDYRK4
Target SynonymsDYRK4FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples293T, A-549, C2C12, HepG2, Jurkat, Rat testisApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 330-480 of human DYRK4 (NP_003836.1).Target SpeciesHuman
Immunogen SequenceTASRRQTFFDSKGFPKNITNNRGKKRYPDSKDLTMVLKTYDTSFLDFLRRCLVWEPSLRMTPDQALKHAWIHQSRNLKPQPRPQTLRKSNSFFPSETRKDKVQGCHHSSRKADEITKETTEKTKDSPTKHVQHSGDQQDCLQHGADTVQLPUniprot IDQ9NR20
Background Information
  • Uniprot Id

    Q9NR20

  • Target Species

    Human

  • Target Name

    DYRK4

  • Target Full Name

    Dual specificity tyrosine-phosphorylation-regulated kinase 4

  • Target Function

    Possible non-essential role in spermiogenesis.

  • Target Subcellular Location

    [Isoform 1]: Cytoplasm.; [Isoform 4]: Cytoplasm. Nucleus.

  • Target Protein Families

    Protein kinase superfamily, CMGC Ser/Thr protein kinase family, MNB/DYRK subfamily

  • Target Synonyms

    DYRK4Dual specificity tyrosine-phosphorylation-regulated kinase 4; EC 2.7.12.1

  • Target Background

    This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

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