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The antibody against DZIP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human DZIP3 (NP_055463.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DZIP3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human DZIP3 (NP_055463.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02640A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DZIP3 |
| Target Synonyms | UURF2; PPP1R66; hRUL138; DZIP3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human DZIP3 (NP_055463.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q86Y13 | Immunogen Sequence |
Uniprot Id
Q86Y13
Target Species
Human
Target Name
DZIP3
Target Full Name
E3 ubiquitin-protein ligase DZIP3
Target Function
E3 Ubiquitin ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Able to specifically bind RNA.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Widely expressed at low level. Highly expressed in skeletal muscle, kidney and heart. Expressed at low level in placenta, lung, brain, liver and pancreas.
Target Synonyms
DZIP3; KIAA0675E3 ubiquitin-protein ligase DZIP3; EC 2.3.2.27; DAZ-interacting protein 3; RING-type E3 ubiquitin transferase DZIP3; RNA-binding ubiquitin ligase of 138 kDa; hRUL138
Target Background
Enables several functions, including phosphatase binding activity; polyubiquitin modification-dependent protein binding activity; and ubiquitin-protein transferase activity. Involved in protein polyubiquitination. Located in cytoplasm.
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