Rabbit anti-Human EPX Polyclonal Antibody

The antibody against EPX was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 400-500 of human EPX (NP_000493.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00278A

Number

Cat.No	ADA-00278A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	EPX
Target Synonyms	EPO; EPP; EPXD; EPX-PEN; EPX	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	human serum, SW620	Application	ELISA, WB

Cat.No

ADA-00278A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

EPX

Target Synonyms

EPO; EPP; EPXD; EPX-PEN; EPX

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

human serum, SW620

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 400-500 of human EPX (NP_000493.1).	Target Species	Human
Immunogen Sequence	TELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLS	Uniprot ID	P11678

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 400-500 of human EPX (NP_000493.1).

Target Species

Human

Immunogen Sequence

TELRRLNPRWNGDKLYNEARKIMGAMVQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVFTLAFRFGHTMLQPFMFRLDSQYRASAPNSHVPLS

Uniprot ID

P11678

Background Information

Uniprot Id

P11678
Target Species

Human
Target Name

EPX
Target Full Name

Eosinophil peroxidase
Target Function

Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.
Target Involvement

Eosinophil peroxidase deficiency (EPXD)
Target Subcellular Location

Cytoplasmic granule. Note=Cytoplasmic granules of eosinophils.
Target Protein Families

Peroxidase family, XPO subfamily
Target Research Area

Cancer
Target Synonyms

Eosinophil peroxidase [Precursor]; Eosinophil peroxidase; Eosinophil peroxidase heavy chain; EPER; EPO; EPP; EPX; EPX PEN; PERE; PERE_HUMAN
Target Background

This gene is a member of the peroxidase gene family and is expressed in eosinophils. The encoded preproprotein is proteolytically processed into covalently attached heavy and light chains to form the mature enzyme, which functions as an oxidant. The enzyme is released at sites of parasitic infection or allergen stimulation to mediate lysis of protozoa or parasitic worms. The gene is found in a gene cluster with other peroxidase genes on chromosome 17. Mutations in this gene result in eosinophil peroxidase deficiency.

Rabbit anti-Human EPX Polyclonal Antibody

Specifications

Immunogen Information

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