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Rabbit anti-Human ETV7 Polyclonal Antibody

The antibody against ETV7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ETV7 (NP_057219.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03119A

The antibody against ETV7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ETV7 (NP_057219.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-03119A ClonalityPolyclonal
Host SpeciesRabbitTarget NameETV7
Target SynonymsTEL2; TELB; TEL-2; ETV7FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, A-431, U-251MG, U-937ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human ETV7 (NP_057219.1).Target SpeciesHuman
Uniprot IDQ9Y603Immunogen Sequence
Background Information
  • Uniprot Id

    Q9Y603

  • Target Species

    Human

  • Target Name

    ETV7

  • Target Full Name

    Transcription factor ETV7

  • Target Function

    Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ETS family

  • Target Tissue Specificity

    Expressed in hematopoietic tissues.

  • Target Synonyms

    ETS related protein Tel2; Ets transcription factor TEL-2b; Ets transcription factor TEL2; ETS translocation variant 7; ets variant 7; ets variant gene 7 (TEL2 oncogene); ets variant gene 7; ETS-related protein Tel2; ETV7; ETV7_HUMAN; TEL 2; Tel related Ets factor ; Tel-related Ets factor; TEL2 ; TEL2 oncogene; TELB; Transcription factor ETV7; Transcription factor Tel 2; Transcription factor Tel-2; TREF

  • Target Background

    The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).

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