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The antibody against EXOC5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 340-610 of human EXOC5 (NP_006535.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against EXOC5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 340-610 of human EXOC5 (NP_006535.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01012A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EXOC5 |
| Target Synonyms | SEC10; HSEC10; SEC10P; PRO1912; SEC10L1; EXOC5 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, MCF7, Mouse lung, THP-1 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 340-610 of human EXOC5 (NP_006535.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O00471 | Immunogen Sequence |
Uniprot Id
O00471
Target Species
Human
Target Name
EXOC5
Target Full Name
Exocyst complex component 5
Target Function
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Target Subcellular Location
Cytoplasm. Midbody.
Target Protein Families
SEC10 family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
EXOC5; SEC10; SEC10L1Exocyst complex component 5; Exocyst complex component Sec10; hSec10
Target Background
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
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