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The antibody against EXTL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 41-330 of human EXTL2 (NP_001430.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against EXTL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 41-330 of human EXTL2 (NP_001430.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04919A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EXTL2 |
| Target Synonyms | EXTR2; EXTL2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse heart | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 41-330 of human EXTL2 (NP_001430.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UBQ6 | Immunogen Sequence |
Uniprot Id
Q9UBQ6
Target Species
Human
Target Name
EXTL2
Target Full Name
Exostosin-like 2
Target Function
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass type II membrane protein.; [Processed exostosin-like 2]: Secreted. Note=A soluble form is found in the serum.
Target Protein Families
Glycosyltransferase 47 family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
4-N-acetylhexosaminyltransferase EXTL2; Alpha 1 4 N acetylhexosaminyltransferase EXTL2; Alpha 1; Alpha GalNAcT EXTL2; Alpha-1; Alpha-GalNAcT EXTL2; Exostoses (multiple) like 2; Exostoses multiple like 2; Exostosin like 2; Exostosin like glycosyltransferase 2; EXT L2; EXT related protein 2 ; EXT-related protein 2; EXTL 2; EXTL2; EXTL2_HUMAN; EXTR 2; EXTR2; Glucuronyl galactosyl proteoglycan 4 alpha N acetylglucosaminyltransferase; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses like 2; Processed exostosin like 2; Processed exostosin-like 2
Target Background
Enables alpha-1, 4-N-acetylgalactosaminyltransferase activity and glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity. Involved in N-acetylglucosamine metabolic process and UDP-N-acetylgalactosamine metabolic process. Located in cytosol; endoplasmic reticulum; and nucleoplasm.
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