Rabbit anti-Human FLVCR2 Polyclonal Antibody

The antibody against FLVCR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FLVCR2 (NP_060261.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01928A

Number

Cat.No	ADA-01928A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	FLVCR2
Target Synonyms	CCT; EPV; PVHH; MFSD7C; SLC49A2; C14orf58; FLVCRL14q; FLVCR2	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549, MCF7, Mouse brain, Mouse liver, Mouse lung	Application	ELISA, WB

Cat.No

ADA-01928A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

FLVCR2

Target Synonyms

CCT; EPV; PVHH; MFSD7C; SLC49A2; C14orf58; FLVCRL14q; FLVCR2

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549, MCF7, Mouse brain, Mouse liver, Mouse lung

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FLVCR2 (NP_060261.2).	Target Species	Human
Immunogen Sequence	MVNEGPNQEESDDTPVPESALQADPSVSVHPSVSVHPSVSINPSVSVHPSSSAHPSALAQPSGLAHPSSSGPEDLSVIKVSRRRWAVVLVFSCYSMCNSF	Uniprot ID	Q9UPI3

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FLVCR2 (NP_060261.2).

Target Species

Human

Immunogen Sequence

MVNEGPNQEESDDTPVPESALQADPSVSVHPSVSVHPSVSINPSVSVHPSSSAHPSALAQPSGLAHPSSSGPEDLSVIKVSRRRWAVVLVFSCYSMCNSF

Uniprot ID

Q9UPI3

Background Information

Uniprot Id

Q9UPI3
Target Species

Human
Target Name

FLVCR2
Target Full Name

Choline/ethanolamine transporter FLVCR2
Target Function

Acts as an importer of heme. Also acts as a transporter for a calcium-chelator complex, important for growth and calcium metabolism.
Target Involvement

Proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome (PVHH)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein.
Target Protein Families

Major facilitator superfamily, Feline leukemia virus subgroup C receptor (TC 2.A.1.28.1) family
Target Tissue Specificity

Expressed in non-hematopoietic tissues, with relative abundant expression in brain, placenta, lung, liver and kidney. Also expressed in hematopoietic tissues (fetal liver, spleen, lymph node, thymus, leukocytes and bone marrow). Found in acidophil cells o
Target Synonyms

FLVCR2; C14orf58Feline leukemia virus subgroup C receptor-related protein 2; Calcium-chelate transporter; CCT
Target Background

This gene encodes a member of the major facilitator superfamily. The encoded transmembrane protein is a calcium transporter. Unlike the related protein feline leukemia virus subgroup C receptor 1, the protein encoded by this locus does not bind to feline leukemia virus subgroup C envelope protein. The encoded protein may play a role in development of brain vascular endothelial cells, as mutations at this locus have been associated with proliferative vasculopathy and hydranencephaly-hydrocephaly syndrome. Alternatively spliced transcript variants have been described.

Rabbit anti-Human FLVCR2 Polyclonal Antibody

Specifications

Immunogen Information

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