Rabbit anti-Human GBP2 Polyclonal Antibody

The antibody against GBP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 410-520 of human GBP2 (NP_004111.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13669A

Number

Cat.No	ADA-13669A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	GBP2
Target Synonyms	GBP2; P2	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-549	Application	ELISA, WB

Cat.No

ADA-13669A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

GBP2

Target Synonyms

GBP2; P2

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-549

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 410-520 of human GBP2 (NP_004111.2).	Target Species	Human
Immunogen Sequence	QDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIEVERIKAESAEAAKKMLEEIQKKNEEMMEQKEK	Uniprot ID	P32456

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 410-520 of human GBP2 (NP_004111.2).

Target Species

Human

Immunogen Sequence

QDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQSLSEKEKAIEVERIKAESAEAAKKMLEEIQKKNEEMMEQKEK

Uniprot ID

P32456

Background Information

Uniprot Id

P32456
Target Species

Human
Target Name

GBP2
Target Full Name

Guanylate-binding protein 2
Target Function

Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
Target Subcellular Location

Cytoplasm. Cytoplasm, perinuclear region. Golgi apparatus membrane. Membrane; Lipid-anchor.
Target Protein Families

TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
Target Research Area

Immunology
Target Synonyms

GBP2Guanylate-binding protein 2; EC 3.6.5.-; GTP-binding protein 2; GBP-2; HuGBP-2; Guanine nucleotide-binding protein 2; Interferon-induced guanylate-binding protein 2
Target Background

This gene belongs to the guanine-binding protein (GBP) family, which includes interferon-induced proteins that can bind to guanine nucleotides (GMP, GDP and GTP). The encoded protein is a GTPase which hydrolyzes GTP, predominantly to GDP. The protein may play a role as a marker of squamous cell carcinomas.

Rabbit anti-Human GBP2 Polyclonal Antibody

Specifications

Immunogen Information

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